Endocrine Abstracts

Background: Endothelial dysfunction may have deleterious effect cardiovascular pathology in diabetic patients.Atrial natriuretic peptide (ANP) exerts beneficial effects on the cardiovascular system in part by exerting antioxidant activity. Recently it was reported that ANP is able to exert an antihypertrophic effect in myocitos at least in part due to inhibition of NADPH oxidase and superoxido generation.It seems that hyperglucemia...

Introduction: The syndrome of late-onset hypogonadism (LOH) is a clinical and biochemical syndrome associated with advancing age male, characterized by typical symptoms and decreased serum concentrations of testosterone, which can affect multiple organ systems and may impair quality of life. The prevalence of LOH syndrome is higher in certain patient groups, obese, diabetic and suffering from erectile dysfunction manifest LOH at higher rates than the general population.<p ...

Introduction: During a normal menstrual cycle, serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol (E2), and progesterone (P4) can vary widely between cycles for the same woman, as well as between different women. Reliable reference values based on the local population are important for correct interpretation of laboratory results.Aims: To evaluate the discrepancy of the results on fertility hormones by two different t...

Moderately elevated body iron stores may be associated with several components of the metabolic syndrome (MetSyn). Elevated serum ferritin levels (Fer) independently predicted incident type 2 diabetes in prospective studies in apparently healthy men and women.Aims: To analyze the association between Fer and components of MetSyn in transsexuals before and after 2-year cross-sex treatment (CST).Methods: Before starting the CST in 90 ...

Elevated serum ferritin levels has been reported in premenopausal women presenting polycystic ovary syndrome (PCOS) and hyperandrogenism, and thus may be involved in the development of insulin resistance, type 2 diabetes y cardiovascular disease. In female-to-male transsexuals (FMTs) PCOS is frequent and this issue has been little studied.Aims: To study the serum ferritin in FMTs with PCOS and their relations with markers of insulin resistance (IR) and m...